New Clinical Trial Investigates Administering MDMA Alongside LSD

Psilocybin Alpha:

It’s not hard to imagine why a bad trip may result in a net disbenefit to a patient seeking to resolve PTSD. Acute anxiety has also been linked to less favourable long-term outcomes in patients treated with LSD (in experimental settings) for depression.

With this in mind, a new Clinical Trial, registered yesterday with ClinicalTrials.gov, seeks to reduce the risk of negative psychedelic effects when taking LSD. The Trial hypothesises that co-administering MDMA with LSD may mitigate the negative psychedelic effects, due to MDMA’s observed ability to reliably induce positive mood.

A clinical trial looking at candyflipping? Simply incredible. And who is behind this, you ask? We don’t know for sure at this point, but Psilocybin Alpha has a hunch:

We believe this Clinical Trial, and its results, belong to MindMed. MindMed holds a licence to 8 Clinical Trials related to LSD with the University Hospital Basel in Switzerland, and recently set-up a European subsidiary in the same country.

Recruitment of the 24 participants has yet to begin. We will keep you updated on the progress and results of this exciting study.

It’s inspiring to see psychedelic research expanding into places that psychonauts have been exploring for decades, like drug combining. Personally, I have found candyflipping to be extremely beneficial for my own entheogenic journeying and am excited to see what sort of results come out of this trial. Assuming MindMed shares the data, that is.

However, I’m not entirely sure that combining MDMA with LSD will be successful at reducing the chance of having a bad trip. While my own experiences with candyflipping have been overwhelmingly positive, I have also been witness to some bad trips that other people went through that involved combining these two drugs. But—to be fair—those particular disasters could have probably been avoided if the set, setting, and dosage had been more carefully planned out, and I do think there is a chance that candyflipping might help mitigate the negative effects of LSD for some people, especially in a controlled clinical setting.